Relationship between Ocular Deviation and Visual Function in Retinitis Pigmentosa

• 宮田, 学

  Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

• 大石, 明生

  Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

• 荻野, 顕

  Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

• 大石, 真秀

  Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

• 長谷川, 智子

  Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

• Nagasaku, Yuko

  Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

• 池田, 華子

  Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

• Ohtsuki, Hiroshi

  Department of Ophthalmology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences

• 辻川, 明孝

  Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine

抄録

In retinitis pigmentosa (RP), peripheral visual-field loss starts in early stages, whereas central vision loss occurs in advanced stages. Sensory strabismus gradually occurs in RP. We investigated the relationship between ocular deviation and visual function and explored for sensory strabismus risk factors in 119 consecutive patients with RP at various stages. We assessed ocular deviation at far and near distances, that is the central visual field, using the mean deviation (MD) value and visual acuity (VA), and the residual binocular field area, using Goldmann perimetry (GP), in 33 patients. The horizontal ocular deviation at near distance was >10° in 30% patients and correlated with residual visual function. Although there was no effective cut-off value for central visual function, a cut-off residual GP area of 40 cm2 distinguished patients with a larger from those with a smaller horizontal ocular deviation at far distance (P = 0.04). Our findings suggest that visual function is negatively associated with ocular deviation in patients with RP and that the sensory strabismus risk is relatively high for patients with a binocular visual field <40 cm2. Thus, screening for ocular alignment may be necessary for patients with RP-associated severe vision loss as part of their comprehensive care.

収録刊行物

• Scientific Reports

  Scientific Reports 8 (1), 2018-10-05

  Springer Nature America, Inc

キーワード

• Multidisciplinary

詳細情報

• CRID: 1050564288161145856
• NII論文ID: 120006529729
• ISSN: 20452322
• DOI: 10.1038/s41598-018-33211-6
• HANDLE: 2433/234699
• Web Site: https://www.nature.com/articles/s41598-018-33211-6.pdf
• Web Site: https://www.nature.com/articles/s41598-018-33211-6
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
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