Diagnostic value of serum ferritin and the risk factors and cytokine profiles of hemophagocytic syndrome following allogeneic hematopoietic cell transplantation

• Nanno, Satoru

• Koh, Hideo

• Nakashima, Yasuhiro

• Katayama, Takako

• Okamura, Hiroshi

• Koh, Shiro

• Yoshimura, Takuro

• Nishimoto, Mitsutaka

• Hayashi, Yoshiki

• Nakamae, Mika

• Hirose, Asao

• Nakane, Takahiko

• Hino, Masayuki

• Nakamae, Hirohisa

Abstract

To examine the diagnostic value of serum ferritin, the associated risk factors, and cytokine profiles of hemophagocytic syndrome (HPS) following allogeneic hematopoietic cell transplantation (allo-HCT), we retrospectively analyzed data from patients undergoing allo-HCT between 2006 and 2012. Of 223 eligible patients, 18 patients developed HPS. A serum ferritin level above 30,000 μg/l was highly specific for the detection of HPS (specificity, 93%). The one-year survival rate for ......

Journal

• Leukemia & Lymphoma

  Leukemia & Lymphoma 58 (7), 1664-1672, 2016-12-06

  Taylor & Francis

Keywords

• 血球貪食症候群
• Hemophagocytic syndrome
• allogeneic hematopoietic cell transplantation
• serum ferritin
• risk factor
• serum cytokine profile

Details

• CRID: 1050001202455082240
• NII Article ID: 120006532429
• ISSN: 10292403
• Web Site: https://dlisv03.media.osaka-cu.ac.jp/il/meta_pub/G0000438repository_10292403-58-7-1664
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles