Obsessions and Compulsions are Strongly Associated with Anxiety and Depressive Symptoms in Childhood and Adolescent Autism Spectrum Disorder

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Background : Autism spectrum disorder (ASD) is highly comorbid with obsessive-compulsive disorder (OCD) in children. Although the association between obsessions and compulsions (OC) and anxiety and depressive symptoms has been acknowledged, some researchers maintain that in individuals with ASD, OC are less related to anxiety symptoms. The purpose of this study was to examine correlations between OC and other factors, including anxiety and depressive symptoms, in both ASD and non-ASD groups. / Methods : We assessed a referral sample of 138 children (aged 9-15 years, 41.3% male). Multiple regression analyses were performed separately for the ASD group and the non-ASD group to examine correlations between OC (as measured by the Leyton Obsessional Inventory-Child Version) and age, sex, socioeconomic status, OCD, attention deficit hyperactivity disorder (ADHD), chronic tic disorder (CTD), Tourette's syndrome (TS), scores on the State-Trait Anxiety Inventory for Children, and scores on the Birleson Depression Self-Rating Scale for Children....

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