Effects of behavioural activation on the neural circuit related to intrinsic motivation

• Mori, Asako

• Okamoto, Yasumasa

• Okada, Go

• Takagaki, Koki

• Takamura, Masahiro

• Jinnin, Ran

• Ichikawa, Naho

• Yamamura, Takanao

• Yokoyama, Satoshi

• Shiota, Syouichi

• Yoshino, Atsuo

• Miyake, Yosie

• Okamoto, Yuri

• Matsumoto, Madoka

• Matsumoto, Kenji

• Yamawaki, Shigeto

Abstract

[Background] Behavioural activation is an efficient treatment for depression and can improve intrinsic motivation. Previous studies have revealed that the frontostriatal circuit is involved in intrinsic motivation; however, there are no data on how behavioural activation affects the frontostriatal circuit. [Aims] We aimed to investigate behavioural activation-related changes in the frontostriatal circuit. [Method] Fifty-nine individuals with subthreshold depression were randomly assigned to either the intervention or non-intervention group. The intervention group received five weekly behavioural activation sessions. The participants underwent functional magnetic resonance imaging scanning on two separate occasions while performing a stopwatch task based on intrinsic motivation. We investigated changes in neural activity and functional connectivity after behavioural activation. [Results] After behavioural activation, the intervention group had increased activation and connectivity in the frontostriatal region compared with the non-intervention group. The increased activation in the right middle frontal gyrus was correlated with an improvement of subjective sensitivity to environmental rewards. [Conclusions] Behavioural activation-related changes to the frontostriatal circuit advance our understanding of psychotherapy-induced improvements in the neural basis of intrinsic motivation. [Declaration of interest] None.

Journal

• BJPsych Open

  BJPsych Open 4 (5), 317-323, 2018-08-02

  Cambridge University Press

Keywords

• Behavioural activation
• intrinsic motivation
• depressive disorders
• imaging
• functional magnetic resonance imaging
• subthreshold depression

Details

• CRID: 1050296265984558976
• NII Article ID: 120006557547
• DOI: 10.1192/bjo.2018.40
• ISSN: 20564724
• Web Site: http://ir.lib.hiroshima-u.ac.jp/00047065
• Web Site: https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S2056472418000406
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN