生体肝移植後患児に対する歯科治療時の全身麻酔5症例の検討

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  • Five cases of general anesthesia for dental treatment in pediatric patients with living-related liver transplantation

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We report 5 cases of general anesthesia for dental treatment in pediatric patients (2 years 6 months oldto6 years old) with living-related liver transplantation. Every patientswere diagnosed to congenital atresia of the bile duct and had living-related livertransplantation (Table 1). The preoperative examination data were normal and they hadno limitation in daily living. Anesthesia was inducted with thiopental sodium in 3 casesand in another 2 cases sevoflurane was used for the induction of anesthesia. Anesthesia was maintained with inhalation anesthetics in every cases, isoflurane with nitrous oxide 2 cases andsevoflurane with nitrous oxide 3 cases. We performed anesthetic management attentively to maintenance of hepatic blood flow, avoidance of hypoxia, infection due to immunosuppressants and liver dysfunction by anesthetic agents. There were nocomplications in perioperative period and they were discharged on the following day.The metabolic rate of isoflurane and sevoflurane in the body were 0.2 % and 3 % respectively.The metabolic rate of sevoflurane is greater than isoflurane , but trifluoroacetic acid is not produced by sevoflurane which may cause liver dysfunction. Desflurane is metabolized more less than isoflurane and it will be a choice of anesthetic agent for the maintenance of general anesthesia. We used nitrous oxide together with isoflurane or sevoflurane in every cases, because of its extremely low metabolic rate and reduction of the volatile anestheticʼs dosage.

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  • 松本歯学

    松本歯学 44 (2), 88-91, 2018-12-31

    松本歯科大学学会

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