Detection of novel gammaherpesviruses from fruit bats in Indonesia

• Wada, Yuji

• Sasaki, Michihito

• Setiyono, Agus

• Handharyani, Ekowati

• Rahmadani, Ibenu

• Taha, Siswatiana

• Adiani, Sri

• Latief, Munira

• Kholilullah, Zainal Abidin

• Subangkit, Mawar

• Kobayashi, Shintaro

• Nakamura, Ichiro

• Kimura, Takashi

• Orba, Yasuko

• Sawa, Hirofumi

抄録

Bats are an important natural reservoir of zoonotic viral pathogens. We previously isolated an alphaherpesvirus in fruit bats in Indonesia, and here establish the presence of viruses belonging to other taxa of the family Herpesviridae. We screened the same fruit bat population with pan-herpesvirus PCR and discovered 68 sequences of novel gammaherpesvirus, designated 'megabat gammaherpesvirus' (MgGHV). A phylogenetic analysis of approximately 3.4 kbp of continuous MgGHV sequences encompassing the glycoprotein B gene and DNA polymerase gene revealed that the MgGHV sequences are distinct from those of other reported gammaherpesviruses. Further analysis suggested the existence of co-infections of herpesviruses in Indonesian fruit bats. Our findings extend our understanding of the infectious cycles of herpesviruses in bats in Indonesia and the phylogenetic diversity of the gammaherpesviruses.

収録刊行物

• Journal of medical microbiology

  Journal of medical microbiology 67 (3), 415-422, 2018-03

  Society for General Microbiology

キーワード

• Gammaherpesvirus
• Fruit bat
• PCR screening
• Long-distance PCR
• Phylogenetic analysis

詳細情報

• CRID: 1050282814037522816
• NII論文ID: 120006633282
• NII書誌ID: AA0070231X
• DOI: 10.1099/jmm.0.000689
• ISSN: 14735644
• ISSN: 00222615
• HANDLE: 2115/74394
• Web Site: https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000689?crawler=true
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN