Gold(I)-Catalyzed Cascade Cyclization Reactions of Allenynes for the Synthesis of Fused Cyclopropanes and Acenaphthenes

• 井貫, 晋輔

  Graduate School of Pharmaceutical Sciences, Kyoto University

• 大石, 真也

  Graduate School of Pharmaceutical Sciences, Kyoto University

• 大野, 浩章

  Graduate School of Pharmaceutical Sciences, Kyoto University

• Ohno, Hiroaki

  Graduate School of Pharmaceutical Sciences, Kyoto University

抄録

A gold‐catalyzed reaction of phenylene‐tethered allenynes with benzofurans gave 1‐(naphth‐1‐yl)cyclopropa[b]benzofuran derivatives, whereas the reaction of 1‐allenyl‐2‐ethynyl‐3‐methylbenzene derivatives in the absence of benzofurans gave acenaphthenes in good yields. These results can be rationalized by nucleophilic attack of the alkyne moiety on an activated allene to form a vinyl cation intermediate.

収録刊行物

• Angewandte Chemie

  Angewandte Chemie 58 (23), 7792-7796, 2019-06-03

  Wiley

キーワード

• allenes
• cascade reactions
• cyclopropanation
• C−H functionalization
• gold

詳細情報

• CRID: 1050282677906838528
• NII論文ID: 120006634622
• NII書誌ID: AA0052535X
• ISSN: 14337851
• ISSN: 15213773
• HANDLE: 2433/241629
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles