Hydroxoiridium-Catalyzed sp^3 C-H Alkylation of Indoline Derivatives with Terminal Alkenes

• Nakamura, Ikumi

• Yamauchi, Daisuke

• Nishimura, Takahiro

Abstract

Direct alkylation of a secondary sp^3 C–H bond of indoline derivatives having a urea moiety with terminal alkenes proceeded in the presence of a hydroxoiridium/1,5-cyclooctadiene catalyst, which would generate an amidoiridium intermediate by the reaction with an urea N–H moiety of the indolines, giving the linear addition products in high yields.

Journal

• Asian Journal of Organic Chemistry

  Asian Journal of Organic Chemistry 7 (7), 1347-1350, 2018-07

  Wiley

Keywords

• アルケン
• C–H活性化
• インドリン
• イリジウム
• alkenes
• C–H activation
• indoline
• iridium
• synthetic methods

Details

• CRID: 1050565162602624640
• NII Article ID: 120006712086
• ISSN: 21935815
• ISSN: 21935807
• DOI: 10.1002/ajoc.201800189
• Web Site: https://dlisv03.media.osaka-cu.ac.jp/il/meta_pub/G0000438repository_21935815-7-7-1347
• Web Site: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fajoc.201800189
• Web Site: https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajoc.201800189
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN