Synthesis of Phenylcyclopropane-Based Secondary Amine Catalysts and Their Applications in Enamine Catalysis

• 武島, 愛夏

  Department of Chemistry, Graduate School of Science, Kyoto University

• 加納, 太一

  Department of Chemistry, Graduate School of Science, Kyoto University

• Maruoka, Keiji

  Department of Chemistry, Graduate School of Science, Kyoto University･Department of Organocatalytic Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto University･School of Chemical Engineering and Light Industry, Guangdong University of Technology

抄録

A novel chiral motif based on a phenylcyclopropane scaffold has been designed, and a facile synthetic route to the key intermediate for the synthesis of phenylcyclopropane-based chiral secondary amines has been developed. Newly synthesized chiral amines function as effective catalysts for several asymmetric reactions through enamine intermediates.

収録刊行物

• Organic Letters

  Organic Letters 21 8071-8074, 2019-10-04

  American Chemical Society (ACS)

キーワード

• Organic Chemistry
• Physical and Theoretical Chemistry
• Biochemistry

詳細情報

• CRID: 1050845763718257664
• NII論文ID: 120006731151
• ISSN: 15237060
• ISSN: 15237052
• DOI: 10.1021/acs.orglett.9b03070
• HANDLE: 2433/244237
• Web Site: https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.9b03070
• 本文言語コード: en
• 資料種別: journal article
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