5) 悪性黒色腫のアミノ酸インバランス療法(シンポジウム 悪性黒色腫の現況と治療, 第477回新潟医学会)

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  • Treatment of Advanced Malignant Melanoma by Amino Acid Imbalance(The Current Status and Treatment of Malignant Melanomas)

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Four patients with advanced melanoma had been treated with the amino acid imbalance therapy using the Phenylalanine-Tyrosin deprived milk by the authors at the surgical unit of Sanjo Saiseikai Hospital and Niigata prefectural Yoshida Hospital within past 15 years. In three of four patients, the therapy showed the remarkable effects. The reduction of the ulcerating melanomas in patient 1 and 2 or the disappearance of the recurrent melanoma of the colon of patient 3 were observed within 1 to 4 weeks after the start of the therapy. In patient 4, who had too extensive dissemination of the melanoma, the therapy could not show the effect. As a result, patient 1. whose melanoma became resectable by the therapy and patient 3, whose recurrent melanoma of the colon was disappeared by the therapy could survive for a long time of 16 and 6 years respectively withont any sign of recurrence of melanoma. But, patient 2, who could not tolerate the therapy, and patient 4 died of melanona at 12 and 2 months after the therapy. Thus, the authors would like to stress the importance of further studies to confirm a possible validity of the Phenylalanine-Tyrosin deprived amino acid imbalance therapy for the treatment of patients with melanoma, because the therapy revealed the appreciable effects on the advanced melanomas of three of four patients to whom chemoimmunotherapy was uneffective by the authors' clinical experiences.

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