Histological and Nuclear Medical Comparison of Inflammation After Hemostasis with Non-Thermal Plasma and Thermal Coagulation

• Ueda, Masashi

• Yamagami, Daiki

• Watanabe, Keiko

• Mori, Asami

• Kimura, Hiroyuki

• Sano, Kohei

• Saji, Hideo

• Ishikawa, Kenji

• Hori, Masaru

• Sakakita, Hajime

• Ikehara, Yuzuru

• Enomoto, Shuichi

Abstract

The objective of this study is to examine the invasiveness of hemostasis by non-thermal plasma (NTP) compared with hemostasis by thermal coagulation (TC). The inflammation recovery process after hemostasis by TC and NTP was compared by using histological methods and nuclear medical molecular imaging. The necrotic areas in the NTP group disappeared after 5 days, whereas they remained 15 days after hemostasis in the TC group. The accumulation of 2-deoxy-2-[F-18] fluoro-D-glucopyranose (F-18-FDG), which reflects the existence of inflammatory cells, was higher in the TC group than in the NTP group on day 15. Thus, this study indicates that hemostasis by NTP is less inflammatory than TC. This report is the first to evaluate inflammation that occurred after hemostasis with medical devices noninvasively.

Journal

• Plasma Processes and Polymers

  Plasma Processes and Polymers 12 (12), 1338-1342, 2015-09-28

Keywords

• hemostasis
• imaging
• inflammation
• non-thermal plasma
• positron emission tomography

Details

• CRID: 1050565163712372480
• NII Article ID: 120006767324
• NII Book ID: AA11976237
• ISSN: 16128850
• Web Site: https://ousar.lib.okayama-u.ac.jp/57491
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • CiNii Articles