Central serous chorioretinopathy with and without steroids : A multicenter survey

• Araki, Takashi

• Ishikawa, Hiroto

• Iwahashi, Chiharu

• Niki, Masanori

• Mitamura, Yoshinori

• Sugimoto, Masahiko

• Kondo, Mineo

• Kinoshita, Takamasa

• Nishi, Tomo

• Ueda, Tetsuo

• Kato, Aki

• Yasukawa, Tsutomu

• Takamura, Yoshihiro

• Gomi, Fumi

書誌事項

タイトル別名

• CSC with and without steroids

抄録

We investigated the rates of the use of steroids in Japanese central serous chorioretinopathy (CSC) cases and differences in the characteristics of CSC with and without steroids. A total of 538 eyes of 477 patients diagnosed with CSC, with 3 months or more of follow-up between April 2013 and June 2017 at 8 institutions. Patients with CSC with more than 3 months of follow-up were identified by OCT and fluorescein angiography at 8 institutions. Data collected included patient demographics, history of corticosteroid medication and smoking, spherical errors, findings of angiography, subfoveal choroidal thickness, and changes through the follow-up period. Differences in these findings were analyzed in cases with and without corticosteroid treatment. Among the 477 patients (344 men,133 women), 74 (15.5%) (39 men, 35 women) underwent current or prior steroid treatment. Cases with steroids were higher age (p = 0.0403) and showed no male prevalence, more bilateral involvement (p < 0.0001), and the affected eyes had multiple pigment epithelial detachment (p <0.0001), more fluorescein leakage sites (p < 0.0001), greater choroidal thickness (p = 0.0287) and a higher recurrence rate (p = 0.0412). Steroids can cause severer CSC through an effect on choroidal vessels and an impairment of retinal pigment epithelium.

収録刊行物

• PLOS ONE

  PLOS ONE 14 (2), e0213110-, 2019-02-28

  PLOS

詳細情報

• CRID: 1050565163352141440
• NII論文ID: 120006812008
• ISSN: 19326203
• Web Site: http://repo.lib.tokushima-u.ac.jp/114339
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles