Changes in high endothelial venules in lymph nodes after vascularized and nonvascularized lymph node transfer in a murine autograft model.

• Ishikawa, Kosuke

• Funayama, Emi

• Maeda, Taku

• Hayashi, Toshihiko

• Murao, Naoki

• Osawa, Masayuki

• Ito, Riri

• Furukawa, Hiroshi

• Oyama, Akihiko

• Yamamoto, Yuhei

Abstract

Vascularized lymph node transfer (LNT) is gaining popularity in the treatment of lymphedema. However, it is unclear whether the vascularization of transferred lymph nodes (LNs) contributes to functional improvement. High endothelial venules (HEVs) are specialized vessels that allow lymphocytes to enter LNs. In this study, we compared the numbers of HEVs and lymphocytes in LNs after vascularized and nonvascularized LNT.

Journal

• Journal of surgical oncology

  Journal of surgical oncology 119 (6), 700-707, 2019-05

  Wiley

Keywords

• laboratory animal model
• lymph nodes
• mice
• transplantation
• vascularized compositeallotransplantation
• Animals
• Autografts
• B-Lymphocytes/metabolism
• Endothelium/blood supply
• Immunohistochemistry
• Lymph Nodes/blood supply
• Lymph Nodes/metabolism
• Lymph Nodes/transplantation
• Lymphedema/surgery
• Mice, Inbred C57BL
• Models, Animal
• T-Lymphocytes/metabolism
• Venules/pathology

Details

• CRID: 1050566774722312704
• NII Article ID: 120006842186
• DOI: 10.1002/jso.25365
• HANDLE: 2115/77806
• ISSN: 10969098
• ISSN: 00224790
• Web Site: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjso.25365
• Web Site: https://onlinelibrary.wiley.com/doi/pdf/10.1002/jso.25365
• Web Site: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/jso.25365
• Web Site: https://onlinelibrary.wiley.com/doi/am-pdf/10.1002%2Fjso.25365
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN