The 12-Item Self-Rating Questionnaire for Depressive Mixed State (DMX-12) for Screening of Mixed Depression and Mixed Features

• Sinzato, Hotaka

• Zamami, Yu

• Kondo, Tsuyoshi

Abstract

For simultaneous screening of mixed features (MF) by DSM-5 and mixed depression (MD) by Benazzi, useful symptoms were extracted from our 12-item dimensional scale for depressive mixed state (DMX-12). Subjects were 190 consecutive cases with major depressive episode (MDE) who visited our clinic. Associations between symptomatological combinations of the DMX-12 and MF or MD were analyzed using receiver operating characteristic (ROC). The rate of MF was 4.2% while that of MD was 22.6%. Eight symptoms (overreactivity, inner tension, racing/crowded thought, impulsivity, irritability, aggression, risk-taking behavior, and dysphoria) with their AUC > 0.6 for ROC curves were specially focused on distinguishing patients with MF or MD from non-mixed patients. By using these 8 symptoms, 40.5% of the overall patients were screened as positive at the same cut-off value (≥13) for both MD and MF. The AUC of ROC curve and sensitivity/specificity were well balanced together with sufficient negative predictive values. The abovementioned 8 symptoms seem to be helpful for primary screening and negative check of DMX with considerable severity during MDE.

論文

Journal

• Brain Sciences

  Brain Sciences 10 (10), 678-, 2020-09-27

  MDPI

Keywords

• depressive mixed state
• screening
• DMX-12
• receiver operating characteristic

Details

• CRID: 1050574201775454208
• NII Article ID: 120006892755
• ISSN: 20763425
• DOI: 10.3390/brainsci10100678
• HANDLE: 20.500.12000/47028
• Web Site: https://u-ryukyu.repo.nii.ac.jp/records/2011172
• Web Site: https://www.mdpi.com/2076-3425/10/10/678/pdf
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN