Clinical and virulence factors related to the 30-day mortality of Klebsiella pneumoniae bacteremia at a tertiary hospital: a case-control study

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  • サンジ ビョウイン デノ ハイエン カンキン キンケツショウ ノ 30ニチ シボウリツ ニ カンレン スル リンショウテキ オヨビ ビョウゲンセイ インシ ノ ケントウ ショウレイ タイショウ ケンキュウ
  • 三次病院での肺炎桿菌菌血症の30日死亡率に関連する臨床的および病原性因子の検討 : 症例対照研究

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Abstract

Purpose: Klebsiella pneumoniae bacteremia is a critical clinical presentation that is associated with high mortality. However, extremely few studies have investigated the virulence factors related to mortality of K. pneumoniae bacteremia in patients. The present study elucidated clinical and virulence factors associated with the 30-day mortality of K. pneumoniae bacteremia at a tertiary hospital. / Methods: The medical records of 129 patients with K. pneumoniae bacteremia admitted to Osaka City University Hospital between January 2012 and December 2018 were retrospectively reviewed. Patient background characteristics, antimicrobial regimens, and prognosis were evaluated. Additionally, virulence factors were assessed using multiplex polymerase chain reaction to elucidate their association with K. pneumoniae....

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