Successful Treatment of a Mixed Neuroendocrine-Nonneuroendocrine Neoplasm of the Colon with Metastases to the Thyroid Gland and Liver
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- Kanazawa, Yuji
- Department of Otolaryngology, Head and Neck Surgery, Kobe City Medical Center General Hospital・Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University
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- Kikuchi, Masahiro
- Department of Otolaryngology, Head and Neck Surgery, Kobe City Medical Center General Hospital・Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University
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- Imai, Yukihiro
- Department of Clinical Pathology, Kobe City Medical Center General Hospital
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- Katakami, Nobuyuki
- Department of Medical Oncology, Kobe City Medical Center General Hospital
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- Kaihara, Satoshi
- Department of Surgery, Kobe City Medical Center General Hospital
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- Shinohara, Shogo
- Department of Otolaryngology, Head and Neck Surgery, Kobe City Medical Center General Hospital
抄録
Patients with mixed neuroendocrine-nonneuroendocrine neoplasms (MiNENs) of the colon have poor prognosis. Herein, we report a patient with MiNEN of the colon with metastases to the liver and the thyroid gland, with long-term survival. A 45-year-old man presented with anterior neck swelling. Histopathological examination of the thyroid tumor revealed neuroendocrine carcinoma (NEC), suggesting that a primary NEC in another organ had metastasized to the thyroid gland. Computed tomography to identify a primary NEC revealed two tumors: one in the liver and one in the transverse colon. A biopsy revealed that the histopathology of the liver and colon tumors was NEC and adenocarcinoma, respectively. Thereafter, the patient underwent surgical resection of the colon tumor and was finally diagnosed as colon MiNEN with metastases to the thyroid and liver. The surgical resection of the metastatic liver tumor was performed after several courses of systemic chemotherapy, and the patient survives presently without any recurrence for approximately seven years after the diagnosis. Surgical resection of each metastatic lesion combined with systematic chemotherapy apparently improved the prognosis of MiNEN of the colon with distant metastases.
収録刊行物
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- Case Reports in Otolaryngology
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Case Reports in Otolaryngology 2020 1-5, 2020
Hindawi Limited
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詳細情報 詳細情報について
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- CRID
- 1050287142219670656
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- NII論文ID
- 120006956722
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- ISSN
- 20906765
- 20906773
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- HANDLE
- 2433/261239
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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