Bakuchiol Is a Phenolic Isoprenoid with Novel Enantiomer-selective Anti-influenza A Virus Activity Involving Nrf2 Activation

• Shoji, Masaki

• Arakaki, Yumie

• Esumi, Tomoyuki

• Kohnomi, Shuntaro

• Yamamoto, Chihiro

• Suzuki, Yutaka

• Takahashi, Etsuhisa

• Konishi, Shiro

• Kido, Hiroshi

• Kuzuhara, Takashi

書誌事項

タイトル別名

• Enantiomer-selective Anti-influenza Activity of Bakuchiol

抄録

Background: Novel therapeutic approaches against influenza are required. Bakuchiol is a phenolic isoprenoid found in Babchi seeds. Results: Bakuchiol enantiomer-selectively inhibited influenza A viral infection and growth and activated the Nrf2 pathway. Conclusion: Bakuchiol showed novel enantiomer-selective anti-influenza viral activity. Significance: The study of bakuchiol will contribute to the development of novel approaches to influenza therapy.

収録刊行物

• Journal of Biological Chemistry

  Journal of Biological Chemistry 290 (46), 28001-28017, 2015-10-07

  The American Society for Biochemistry and Molecular Biology

詳細情報

• CRID: 1050850092109826432
• NII論文ID: 120006959751
• NII書誌ID: AA1202441X
• ISSN: 00219258
• Web Site: http://repo.lib.tokushima-u.ac.jp/115492
• 本文言語コード: en
• 資料種別: journal article
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