Nucleotide and Amino Acid Sequences in The PreM Region of A Japanese Encephalitis Virus Strain Isolated from A Pool of Aedes albopictus and Ae. butleri Mosquitoes Captured in Peninsula Malaysia in 1992

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One strain of Japanese encephalitis (JE) virus isolated from a pool of Ae. albopictus and Ae. butleri in Peninsula Malaysia in 1992 was sequenced for its PreM gene region, by direct sequencing the product from reverse transcriptase polymerase chain reaction (RTPCR). The sequence in the length of 240 nucleotides (nt) and deduced amino acid (AA) sequence were compared with the published sequences for the various JE virus strains from different geographical regions. This virus strain, MaSAr39692, showed a close homology to the strains from epidemic areas such as Japan, China, Taiwan, Sri Lanka and India. The homology between MaSAr39692 and JaOArS982 strain, for which entire genome sequence was first determined, was 95.8%, with 10 nt and 3 AA sequence divergence.

熱帯医学 Tropical medicine 36(2). p51-56, 1994

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