Molecular Characterization and Clinical Evaluation of Dengue Outbreak in 2002 in Bangladesh
-
- Islam Mohammed Alimul
- Department of Virology, Institute of Tropical Medicine, Nagasaki University, Japan Core Research for Evolutional Science and Technology (CREST), Japan
-
- Ahmed Muzahed Uddin
- Department of Medicine, Faculty of Veterinary Science, Bangladesh Agricultural University, Bangladesh
-
- Begum Nasima
- Shaheed Suhrawardi Hospital, Bangladesh
-
- Chowdhury Naseem Akhtar
- Shaheed Suhrawardi Hospital, Bangladesh
-
- Khan Afjal Hossain
- Department of Virology, Institute of Tropical Medicine, Nagasaki University, Japan
-
- Parquet Maria del Carmen
- Department of Virology, Institute of Tropical Medicine, Nagasaki University, Japan
-
- Bipolo Sophie
- Department of Virology, Institute of Tropical Medicine, Nagasaki University, Japan
-
- Inoue Shingo
- Department of Virology, Institute of Tropical Medicine, Nagasaki University, Japan
-
- Hasebe Futoshi
- Department of Virology, Institute of Tropical Medicine, Nagasaki University, Japan
-
- Suzuki Yasuo
- Department of Biochemistry, School of Pharmaceutical Science, University of Shizuoka, Japan Core Research for Evolutional Science and Technology (CREST), Japan
-
- Morita Kouichi
- Department of Virology, Institute of Tropical Medicine, Nagasaki University, Japan Core Research for Evolutional Science and Technology (CREST), Japan
この論文をさがす
抄録
<p>During the febrile illness epidemic in Bangladesh in 2002, 58 people died out of the 6,132 affected. Two hundred hospitalized patients were analyzed clinically, serologically and virologically to determine the features of this dengue infection. Among the 10- to 70-year-old age group of the 200 clinically suspected dengue patients, 100 (50%) were confirmed as dengue cases by virus isolation and dengue IgM-capture ELISA. Of the 100 dengue-confirmed cases, the mean age was 29.0 (±12.4). The possible dengue secondary infection rate determined by Flavivirus IgG-indirect ELISA was 78% in 2002. Eight dengue virus strains were isolated, representing the first dengue virus isolation in the country, and all of the strains were dengue virus type-3 (DEN-3). Sequence data for the envelope gene of the DEN-3 Bangladeshi isolates were used in a phylogenetic comparison with DEN-3 from other countries. A phylogenetic analysis revealed that all 8 strains of DEN-3 were clustered within a well-supported independent sub-cluster of genotype II and were closely related to the Thai isolates from the 1990s. Therefore, it is likely that the currently circulating DEN-3 viruses entered Bangladesh from neighboring countries.</p>
収録刊行物
-
- Japanese Journal of Infectious Diseases
-
Japanese Journal of Infectious Diseases 59 (2), 85-91, 2006-04-28
国立感染症研究所
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390298986213514752
-
- NII論文ID
- 120006983661
-
- NII書誌ID
- AA1132885X
-
- ISSN
- 18842836
- 13446304
-
- HANDLE
- 10069/22630
-
- NDL書誌ID
- 7890504
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可