Adherence ability of Staphylococcus epidermidis on prosthetic biomaterials: an in vitro study
Abstract
Bacterial adhesion to the surface of biomaterials is an essential step in the pathogenesis of implant-related infections. In this in vitro research, we evaluated the ability of Staphylococcus epidermidis to adhere to the surface of solid biomaterials, including oxidized zirconium-niobium alloy (Oxinium), cobalt-chromium-molybdenum alloy, titanium alloy, commercially pure titanium, and stainless steel, and performed a biomaterial-to-biomaterial comparison. The test specimens were physically analyzed to quantitatively determine the viable adherent density of the S. epidermidis strain RP62A (American Type Culture Collection [ATCC] 35984). Field emission scanning electron microscope and laser microscope examination revealed a featureless, smooth surface in all specimens (average roughness < 10 nm). The amounts of S. epidermidis that adhered to the biomaterial were significantly lower for Oxinium and the cobalt-chromium-molybdenum alloy than for commercially pure titanium. These results suggest that Oxinium and cobalt-chromium-molybdenum alloy are less susceptible to bacterial adherence and are less inclined to infection than other materials of a similar degree of smoothness.
International Journal of Nanomedicine, 8, pp.3955-3961; 2013
Journal
-
- International Journal of Nanomedicine
-
International Journal of Nanomedicine 8 3955-3961, 2013-10-14
Dove Medical Press Ltd.
- Tweet
Details 詳細情報について
-
- CRID
- 1050568772216877184
-
- NII Article ID
- 120006986062
-
- ISSN
- 11782013
-
- HANDLE
- 10069/33974
-
- Text Lang
- en
-
- Article Type
- journal article
-
- Data Source
-
- IRDB
- Crossref
- CiNii Articles
- KAKEN