Regioselective Synthesis of 2,4-Differentially Arylated Pyrroles and Its Application to The Synthesis of Lamellarins

• Fukuda, Tsutomu

• Anzai, Mizuho

• Iwao, Masatomo

Abstract

An efficient method for the synthesis of 2,4-differentially arylated pyrroles has been developed via stepwise palladium-catalyzed Suzuki-Miyaura coupling of N-benzenesulfonyl-4-bromo-2-iodopyrrole with different arylboronic acids. This method has been applied to the new synthesis of the marine natural products lamellarins.

HETEROCYCLES, 93(2), pp.593-612; 2016

Journal

• HETEROCYCLES

  HETEROCYCLES 93 (2), 593-612, 2016

  日本複素環化学研究所

Keywords

• Organic Chemistry
• Pharmacology
• Analytical Chemistry

Details

• CRID: 1050005822263753088
• NII Article ID: 120006987526
• NII Book ID: AA00663739
• ISSN: 03855414
• DOI: 10.3987/com-15-s(t)49
• HANDLE: 10069/37531
• NDL BIB ID: 028098151
• Web Site: https://nagasaki-u.repo.nii.ac.jp/records/2324
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I028098151
• Text Lang: en
• Article Type: journal article
• Data Source:
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN