Entamoeba Encystation: New Targets to Prevent the Transmission of Amebiasis

• Mi-ichi, Fumika

• Yoshida, Hiroki

• Hamano, Shinjiro

抄録

mebiasis is caused by Entamoeba histolytica infection and can produce a broad range of clinical signs, from asymptomatic cases to patients with obvious symptoms. The current epidemiological and clinical statuses of amebiasis make it a serious public health problem worldwide. The Entamoeba life cycle consists of the trophozoite, the causative agent for amebiasis, and the cyst, the form responsible for transmission. These two stages are connected by “encystation” and “excystation.” Hence, developing novel strategies to control encystation and excystation will potentially lead to new measures to block the transmission of amebiasis by interrupting the life cycle of the causative agent. Here, we highlight studies investigating encystation using inhibitory chemicals and categorize them based on the molecules inhibited. We also present a perspective on new strategies to prevent the transmission of amebiasis.

PLOS Pathogens, 12(10), e1005845; 2016

収録刊行物

• PLOS Pathogens

  PLOS Pathogens 12 (10), e1005845-, 2016-10-20

  Public Library of Science

詳細情報

• CRID: 1050287297252288640
• NII論文ID: 120006987617
• ISSN: 15537374
• HANDLE: 10069/37341
• Web Site: https://nagasaki-u.repo.nii.ac.jp/records/2143
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles