Exploring ligand binding pathways on proteins using hypersound-accelerated molecular dynamics

• 荒木, 望嗣

  Graduate School of Medicine, Kyoto University

• 松本, 篤幸

  Medical Sciences Innovation Hub Program, RIKEN Cluster for Science, Technology and Innovation Hub

• Bekker, Gert-Jan

  Institute for Protein Research, Osaka University

• 井阪, 悠太

  Research and Development Group for In Silico Drug Discovery, Center for Cluster Development and Coordination (CCD), Foundation for Biomedical Research and Innovation at Kobe (FBRI)

• 寒河江, 由香里

  Graduate School of Medicine, Kyoto University

• 神谷, 成敏

  Graduate School of Simulation Studies, University of Hyogo

• 奥野, 恭史

  Graduate School of Medicine, Kyoto University; Medical Sciences Innovation Hub Program, RIKEN Cluster for Science, Technology and Innovation Hub

抄録

生体分子の動きを効率的に捉えるシミュレーション技術を開発 --超高周波超音波照射によってタンパク質と医薬品の結合計算を加速--. 京都大学プレスリリース. 2021-05-28.

収録刊行物

• Nature Communications

  Nature Communications 12 2793-, 2021

  Springer Nature

キーワード

• Computational biophysics
• Drug development
• Single-molecule biophysics

詳細情報

• CRID: 1050288292953170560
• NII論文ID: 120007041708
• DOI: 10.1038/s41467-021-23157-1
• ISSN: 20411723
• HANDLE: 2433/263135
• Web Site: https://www.nature.com/articles/s41467-021-23157-1.pdf
• Web Site: https://www.nature.com/articles/s41467-021-23157-1
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN