Cytomegalovirus (CMV) colitis associated with chemotherapy and molecular targeted therapy for gynecologic cancer: A case report of ovarian cancer

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Cytomegalovirus (CMV) colitis associated with chemotherapy for gynecologic cancer is rare. We report a case of CMV colitis linked to treatment with paclitaxel/carboplatin (TC) and bevacizumab (BEV) for ovarian cancer. Our patient was a 59-year-old woman who completed one course of TC chemotherapy and one course of TC + BEV as neoadjuvant chemotherapy for advanced ovarian cancer. On the 7th day of TC + BEV therapy, she visited our hospital for continuous diarrhea, abdominal pain, and melena. Grade 4 neutropenia and fever were also detected. She was diagnosed as CMV colitis via colonoscopy and histopathological examination. This is the first case report of CMV colitis complicated by chemotherapy-induced febrile neutropenia during the treatment for gynecologic cancer.

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