Ergothioneine production with Aspergillus oryzae

• 大津, 厳生

• Takusagawa, Shun

• Satoh, Yasuharu

• Dairi, Tohru

抄録

To establish a reliable and practical ergothioneine (ERG) supply, we employed fermentative ERG production using Aspergillus oryzae, a fungus used for food production. We heterologously overexpressed the egt-1 and -2 genes of Neurospora crassa in A. oryzae and succeeded in producing ERG (231.0 mg/kg of media, which was 20 times higher than the wild type). Abbreviations: ERG: ergothioneine; HER: hercynine; Cys-HER: hercynylcysteine-sulfoxide; SAM: S-adenosylmethionine; SAH: S-adenosylhomocysteine; l-His: l-histidine; l-Cys: l-cysteine; LC-ESI-MS: liquid chromatography-electrospray ionization-mass spectrometry

収録刊行物

• Bioscience, biotechnology, and biochemistry

  Bioscience, biotechnology, and biochemistry 83 (1), 181-184, 2018-10

  TAYLOR & FRANCIS

キーワード

• Organic Chemistry
• Molecular Biology
• Applied Microbiology and Biotechnology
• General Medicine
• Biochemistry
• Analytical Chemistry
• Biotechnology

詳細情報

• CRID: 1050001339199081984
• NII論文ID: 120007133324
• NII書誌ID: AA10824164
• ISSN: 09168451
• ISSN: 13476947
• DOI: 10.1080/09168451.2018.1527210
• HANDLE: 2241/00157838
• Web Site: https://tsukuba.repo.nii.ac.jp/records/52417
• Web Site: http://academic.oup.com/bbb/article-pdf/83/1/181/36826333/bbb0181.pdf
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN