A muscle fatigue-like contractile decline was recapitulated using skeletal myotubes from Duchenne muscular dystrophy patient-derived iPSCs

• 内村, 智也

  Center for iPS Cell Research and Application (CiRA), Kyoto University; Takeda-CiRA Joint Program

• 浅野, 豪文

  Department of Cell Biology, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University; The Center for Brain Integration Research, Tokyo Medical and Dental University

• 中田, 隆夫

  Department of Cell Biology, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University; The Center for Brain Integration Research, Tokyo Medical and Dental University

• 堀田, 秋津

  Center for iPS Cell Research and Application (CiRA), Kyoto University; Takeda-CiRA Joint Program

• 櫻井, 英俊

  Center for iPS Cell Research and Application (CiRA), Kyoto University; Takeda-CiRA Joint Program

抄録

デュシェンヌ型筋ジストロフィー患者由来iPS細胞を用いて、筋疲労に似た収縮力低下を培養細胞で再現する事に成功. 京都大学プレスリリース. 2021-06-07.

収録刊行物

• Cell Reports Medicine

  Cell Reports Medicine 2 (6), 100298-, 2021-06

  Elsevier B.V.

キーワード

• EFS training
• muscle overuse
• optogenetics
• high-throughput
• induced pluripotent stem cells
• skeletal muscle cells
• mature myotube differentiation model
• Duchenne muscular dystrophy
• contractile dysfunction

詳細情報

• CRID: 1050852271156762368
• NII論文ID: 120007142199
• DOI: 10.1016/j.xcrm.2021.100298
• HANDLE: 2433/263987
• ISSN: 26663791
• Web Site: https://api.elsevier.com/content/article/PII:S2666379121001312?httpAccept=text/xml
• Web Site: https://api.elsevier.com/content/article/PII:S2666379121001312?httpAccept=text/plain
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • Crossref
  • CiNii Articles
  • KAKEN