NADPH is important for isobutanol tolerance in a minimal medium of <i>Saccharomyces cerevisiae</i>

• Yoshikawa, Yuki

• Nasuno, Ryo

• Takagi, Hiroshi

書誌事項

タイトル別名

• NADPH is important for isobutanol tolerance in a minimal medium of Saccharomyces cerevisiae

抄録

We showed that the isobutanol sensitivity in glucose-6-phosphate dehydrogenase-deficient cells of the yeast Saccharomyces cerevisiae was rescued by an alternative NADPH producer, acetaldehyde dehydrogenase, but not in the cells lacking 6-phosphogluconate dehydrogenase. This phenotype correlated with the intracellular NADPH/NADP+ ratio in yeast strains. Our findings indicate the importance of NADPH for the isobutanol tolerance of yeast cells.

収録刊行物

• Bioscience, Biotechnology and Biochemistry

  Bioscience, Biotechnology and Biochemistry 85 (9), 2084-2088, 2021-06-25

  日本農芸化学会

キーワード

• Saccharomyces cerevisiae
• pentose phosphate pathway
• NADPH
• 6-phosphogluconate dehydrogenase
• isobutanol tolerance

詳細情報

• CRID: 1050577309352749952
• NII論文ID: 120007168291
• ISSN: 13476947
• DOI: 10.1093/bbb/zbab115
• HANDLE: 10061/14523
• Web Site: https://naist.repo.nii.ac.jp/records/9376
• Web Site: http://academic.oup.com/bbb/advance-article-pdf/doi/10.1093/bbb/zbab115/39502862/zbab115.pdf
• Web Site: http://academic.oup.com/bbb/article-pdf/85/9/2084/39891160/zbab115.pdf
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
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