Metal-Containing Schiff Base/Sulfoxide Ligands for Pd(II)-Catalyzed Asymmetric Allylic C-H Aminations

• Bunno, Youka

• Tsukimawashi, Yuta

• Kojima, Masahiro

• Yoshino, Tatsuhiko

• Matsunaga, Shigeki

抄録

Metal-containing Schiff base/sulfoxides were developed as chiral ligands for Pd(II)-catalyzed asymmetric intramolecular allylic C-H amination reactions. The use of metal-containing Schiff base ligands allows tuning the selectivity and reactivity of the Pd(II)-catalyst, whereby a Schiff base-Cu(II)/sulfoxide ligand in combination with Pd(OAc)(2) showed the best performance. Both internal and terminal alkenes were applicable, and the C-H amination products were obtained in up to 91:9 er.

収録刊行物

• ACS catalysis

  ACS catalysis 11 (5), 2663-2668, 2021-02-12

  American Chemical Society

キーワード

• asymmetric catalysis
• asymmetric synthesis
• allylic C-H functionalization
• palladium
• Schiff base ligand

詳細情報

• CRID: 1050854107994410880
• NII論文ID: 120007191784
• DOI: 10.1021/acscatal.0c05261
• HANDLE: 2115/84165
• ISSN: 21555435
• Web Site: https://pubs.acs.org/doi/pdf/10.1021/acscatal.0c05261
• 本文言語コード: en
• 資料種別: journal article
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