Differences in Developing Intestinal Microbiota between Allergic and Non-Allergic Infants: A Pilot Study in Japan
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The bacterial compositions of feces were monitored in the first 2 months for 15 infants born in Japan, including eight subjects who developed allergy by the age of 2 years. Primer sets targeting six predominant bacterial groups in the infant intestine, <I>Bacteroidaceae</I>, <I>Enterobacteriaceae</I>, bifidobacteria, enterococci, lactobacilli, and the <I>Clostridium perfringens</I> group, were used for real-time PCR to quantitate each population in the feces. The population of <I>Bacteroidaceae</I> was significantly higher in the allergic group at the ages of 1 month (<I>P</I>=0.03) and 2 months (<I>P</I>=0.05) than in the non-allergic group, while no statistically significant difference was observed for the other bacterial populations.
- Bioscience, Biotechnology, and Biochemistry
Bioscience, Biotechnology, and Biochemistry 71(9), 2338-2342, 2007
Japan Society for Bioscience, Biotechnology, and Agrochemistry