Degradation of PrP^Scby Keratinolytic Protease from<i>Nocardiopsis</i>sp. TOA-1

• MITSUIKI Shinji

  Department of Applied Chemistry and Biochemistry, Kyushu Sangyo University

• HUI Zhao

  Department of Veterinary Physiology, Kagoshima University

• MATSUMOTO Daishi

  Department of Applied Chemistry and Biochemistry, Kyushu Sangyo University

• SAKAI Masashi

  Department of Applied Chemistry and Biochemistry, Kyushu Sangyo University

• MORIYAMA Yasushi

  Fundamental Research Center, TOTO Ltd.

• FURUKAWA Kensuke

  Division of Bioresource and Bioenvironmental Sciences, Kyushu University

• KANOUCHI Hiroaki

  Department of Biochemistry, Kawasaki Medical School

• OKA Tatsuzo

  Department of Veterinary Physiology, Kagoshima University

書誌事項

タイトル別名

• Degradation of PrPSc by Keratinolytic Protease from Nocardiopsis sp. TOA-1

抄録

A keratinolytic alkaline proteae (NAPase) from Nocardiopsis sp. TOA-1 degraded a scrapie prion without any chemical or physical treatment. Optimal temperature and pH were 60 °C and above pH 10.0. The scrapie prion was completely degraded within 3 min under optimal conditions.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 70 (5), 1246-1248, 2006

  公益社団法人 日本農芸化学会

キーワード

• prion
• alkaline protease
• keratinase
• <I>Nocardiopsis</I> sp.

詳細情報

• CRID: 1390282681453733760
• NII論文ID: 130000029906
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.70.1246
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 7926470
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7926470
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.70.1246
• 本文言語コード: en
• データソース種別:
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  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可