Comparative Effect of Repeated Ingestion of Difructose Anhydride 3 and Palatinose on the Induction of Gastrointestinal Symptoms in Humans
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- TAMURA Akiko
- Central Research Laboratory, FANCL Co., Ltd. Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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- SHIOMI Takuya
- Central Research Laboratory, FANCL Co., Ltd.
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- TAMAKI Noriko
- Central Research Laboratory, FANCL Co., Ltd.
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- SHIGEMATSU Norihiro
- Central Research Laboratory, FANCL Co., Ltd.
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- TOMITA Fusao
- Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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- HARA Hiroshi
- Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
書誌事項
- タイトル別名
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- Comparative Effect of Repeated Ingestion of Difructose Anhydride III and Palatinose on the Induction of Gastrointestinal Symptoms in Humans
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抄録
We evaluated the safety and change in fermentability from repeated ingestion of difructose anhydride III (DFAIII) in humans. A randomized controlled single-blind crossover study with thirteen subjects was conducted. Each subject ingested 5 g of DFAIII or palatinose daily for 12 days, before and after which the subject was loaded with 10 g of DFAIII and had breath hydrogen measured from 0 to 9 h (DL test) to evaluate the fermentability of DFAIII. The defecation frequency and abdominal symptom score were the same between each ingestion period. Moreover, DFAIII ingestion had no influence on blood test results. Only the breath hydrogen excretion in post-DFAIII ingestion was slightly higher at h 8 than the pre-ingestion. Consequently, repeated ingestion of DFAIII for 12 days was as safe as palatinose ingestion, especially with respect to abdominal symptoms and blood test results, and its high resistance to enterobacterial fermentation in humans was not impaired.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 68 (9), 1882-1887, 2004
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390282681449704448
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- NII論文ID
- 130000030597
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- NII書誌ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 7101124
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- PubMed
- 15388963
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可