チャイニーズハムスター培養細胞におけるロテノン誘発核内倍加の有糸分裂〔英文〕

• MATSUMOTO Kyomu

  Laboratory of Genetic Toxicology, Institute of Environmental Toxicology

• OHTA Toshihiro

  Laboratory of Genetic Toxicology, Institute of Environmental Toxicology

書誌事項

タイトル別名

• Mitosis of rotenone-induced endoreduplication in Chinese hamster cells.
• チャイニーズ ハムスター バイヨウ サイボウ ニ オケル ロテノン ユウハツ カ

抄録

Endoreduplication was induced by rotenone with an extremely high frequency (approximately 90% of all the metaphases) in cultured Chinese hamster cells. Endoreduplicated cells were fixed without colchicine or hypotonic treatment, and chromosomal configurations were examined in various mitotic stages. The two sister chromosomes of each diplochromosome at late prophase were widely separated except the centromeric region, but they became gradually paired along the total length as the cell cycle progressed to metaphase. The anaphase cells underwent multipolar division, resulting in three or four aneuploid daughter cells. Indirect immunofluorescence staining using anti-β tubulin antibody revealed tripolar or tetrapolar spindles and unusual equatorial plates.<br>

収録刊行物

• 遺伝学雑誌

  遺伝学雑誌 68 (3), 185-194, 1993

  日本遺伝学会

キーワード

• Genetics
• General Medicine

詳細情報

• CRID: 1390282680420134528
• NII論文ID: 130000057087
• NII書誌ID: AA00690924
• DOI: 10.1266/jjg.68.185
• ISSN: 18805787
• ISSN: 0021504X
• NDL書誌ID: 3841294
• PubMed: 8251185
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I3841294
• Web Site: http://www.jstage.jst.go.jp/article/jjg/68/3/68_3_185/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可