トラフグに寄生するエラムシ<i>Heterobothrium okamotoi</i> に対するフェバンテルの駆虫効果

  • 木村 武志
    Kumamoto Prefectural Fisheries Development Division
  • 鮫島 守
    Kumamoto Prefectural Fisheries Development Division
  • 野村 昌功
    Kumamoto Prefectural Fisheries Research Center
  • 森田 淳
    Agri-Vet Research, Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd.
  • 溝口 秀城
    Animal Helth Department, Research & Development Agriculture & Veternary Division, Meiji Seika Kaisha, Ltd.
  • 石原 守
    Agri-Vet Research, Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd.

書誌事項

タイトル別名
  • Efficacy of Orally Administered Febantel against Monogenean Heterobothrium okamotoi infection of Cultured Tiger Puffer Takifugu rubripes

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抄録

We examined the efficacy of febantel against the infection of the diclidophorid monogenean Heterobothrium okamotoi in cultured tiger puffer Takifugu rubripes. Febantel is a prodrug of fenbendazole, a benzimidazole drug, which is widely used in the field of veterinary medicine. Febantel was metabolized to fenbendazole in tiger puffer just like veterinary animals for oral administration. At the doses of 12.5 mg/kg and 25 mg/kg for 5 days, and 50 mg/kg for 3 days, 88%, 96% and 94%, respectively, of mature worms, and 97%, 95% and 97%, respectively, of immature worms were eradicated at 22-23°C. These results suggest that febantel has high anti-H. okamotoi activity.

収録刊行物

  • 魚病研究

    魚病研究 41 (4), 147-151, 2006

    日本魚病学会

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