Usefulness of Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography in a Patient With Takayasu's Arteritis Associated With Antiphospholipid Syndrome

• Kaku Bunji

  Division of Cardiology, Department of Internal Medicine, Ishikawa Prefectural Central Hospital

• Higuchi Takahiro

  Division of Cardiology and Radiology, Kanazawa Cardiovascular Hospital, Kanazawa University

• Kanaya Hounin

  Division of Cardiology, Department of Internal Medicine, Ishikawa Prefectural Central Hospital

• Horita Yuki

  Division of Cardiology, Department of Internal Medicine, Ishikawa Prefectural Central Hospital

• Yamazaki Tsukasa

  Division of Cardiology, Department of Internal Medicine, Ishikawa Prefectural Central Hospital

• Uno Yoshihide

  Division of Cardiology, Department of Internal Medicine, Ishikawa Prefectural Central Hospital

• Itoh Hideki

  Division of Cardiology, Department of Internal Medicine, Ishikawa Prefectural Central Hospital

• Namura Masanobu

  Division of Cardiology and Radiology, Kanazawa Cardiovascular Hospital, Kanazawa University

• Shimizu Masami

  Division of Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University

抄録

A 36-year-old woman was admitted for recurring chest pain and hemoptysis. Blood pressure in the right and left arms was equal, and no murmurs or bruits were heard. Body temperature was normal on admission and remained within the normal range during the hospital stay. C-reactive protein was slightly elevated (2.3 mg/dL) and lupus anticoagulant was positive. Angiography showed no abnormality of the aorta or its branches, but the left pulmonary artery showed occlusion at the proximal portion. Computed tomography (CT) revealed segmental wall thickening of the thoracic aorta. Fluorine-18-fluorodeoxyglucose positron emission tomography (¹⁸FDG PET) showed high uptake in the proximal portion of the left pulmonary artery and in the thoracic aorta with wall thickening on CT. Based on these findings, a diagnosis of Takayasu's arteritis associated with antiphospholipid syndrome was made and high-dose steroid therapy (prednisolone 30 mg/day) was started. Two months later, the C-reactive protein level had decreased from 2.3 mg/dL to 1.1 mg/dL, and both the focal wall thickening and ¹⁸FDG uptake of the thoracic aorta were decreased. ¹⁸FDG PET was useful for evaluating the efficacy of the steroid therapy in addition to making a diagnosis of Takayasu's arteritis associated with antiphospholipid syndrome. <br>

収録刊行物

• International Heart Journal

  International Heart Journal 47 (2), 311-317, 2006

  一般社団法人 インターナショナル・ハート・ジャーナル刊行会

キーワード

• Takayasu's arteritis
• Antiphospholipid syndrome
• Positron-emission tomo-graphy

詳細情報

• CRID: 1390282680202530560
• NII論文ID: 130000068731
• NII書誌ID: AA12013242
• DOI: 10.1536/ihj.47.311
• ISSN: 13493299
• ISSN: 13492365
• HANDLE: 2297/28374
• Web Site: https://kanazawa-u.repo.nii.ac.jp/records/14508
• Web Site: http://www.jstage.jst.go.jp/article/ihj/47/2/47_2_311/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2006312449
• 本文言語コード: en
• データソース種別:
  • JaLC
  • IRDB
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可