Development of a Signal-Averaged Vector-Projected 187-Channel High-Resolution Electrocardiogram for the Evaluation of the Spatial Location of High-Frequency Potentials and Abnormal Ventricular Repolarization

• Nakai Kenji

  Department of Laboratory Medicine, Iwate Medical University

• Tsuboi Junichi

  Department of Cardiovascular Surgery, Iwate Medical University

• Okabayashi Hitoshi

  Department of Cardiovascular Surgery, Iwate Medical University

• Fukushima Akimune

  Department of Obstetrics and Gynecology, Iwate Medical University

• Itoh Manabu

  ICS, Co., Ltd. Iwate

• Kawata Hiroshi

  Division of Medical Engineering and Clinical Investigation Institute of Development, Aging and Cancer, Tohoku University

• Miyake Fumihiko

  Department of Cardiology, St. Marianna University School of Medicine

• Kasanuki Hiroshi

  Department of Cardiology, Tokyo Women's Medical College

抄録

Noninvasive risk stratification is important for screening for lethal arrhythmia.<br> We developed a 187-channel signal-averaged vector-projected high-resolution electrocardiograph (187-ch SAVP-ECG) for detecting abnormalities in the spatial location of ventricular high-frequency late potentials (HFLPs) and ventricular repolarization. <br> The subjects consisted of 30 normal controls (CONTROL) and 13 patients with HFLPs (6 with myocardial infarction [MI], 6 with cardiomyopathy, and 1 with Brugada syndrome). The modified X, Y, Z-lead ECG and the synthesized signals from vector-projected 187-channel ECGs were amplified and passed through a digital filter. We calculated the integration of the HFLPs area between QRS_end and 30 ms before QRS_end. The integrated HFLPs map was superimposed on the corrected recovery time (RTc) and Tpeak-end dispersion maps composed by 187-ch SAVP-ECG. All patients received an examination by 64-channel magnetocardiography (64-ch MCG) on the same day. <br> The spatial distribution of HFLPs by the 187-ch SAVP-ECG map was in agreement with the location of increased RT dispersion in MI. The spatial distribution of HFLPs in DCM demonstrated a wide variety of patterns. Interestingly, the spatial distribution of HFLPs in cases with ARVC was located at around a right ventricular outflow region. The spatial distribution of HFLPs by 187-ch SAVP-ECG was in agreement with those determined by 64-ch MCG. <br> The 187-ch SAVP-ECG might be useful for evaluating the spatial distribution of nonuniform conduction and ventricular repolarization heterogeneity. <br>

収録刊行物

• International Heart Journal

  International Heart Journal 48 (6), 701-713, 2007

  一般社団法人 インターナショナル・ハート・ジャーナル刊行会

キーワード

• Vector-projection
• Body surface mapping
• High-resolution ECG
• Late potentials
• Ventricular repolarization
• Myocardial infarction
• Dilated cardiomyopathy

詳細情報

• CRID: 1390282680202584704
• NII論文ID: 130000068982
• DOI: 10.1536/ihj.48.701
• ISSN: 13493299
• ISSN: 13492365
• Web Site: http://www.jstage.jst.go.jp/article/ihj/48/6/48_6_701/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008144774
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可