Budd-Chiari Syndrome Associated with Hypereosinophilic Syndrome; A Case Report

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  • Inoue Ai
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city
  • Michitaka Kojiro
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city
  • Shigematsu Shuichiro
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city Internal Medicine, Saiseikai Matsuyama Hospital
  • Konishi Ichiro
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city
  • Hirooka Masashi
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city
  • Hiasa Yoichi
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city
  • Matsui Hidetaka
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city
  • Matsuura Bunzo
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city
  • Horiike Norio
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city
  • Hato Takaaki
    Department of Bioregulatory Medicine, Ehime University Graduate School of Medicine, Toon-city
  • Miyaoka Hiroaki
    Internal Medicine, Saiseikai Matsuyama Hospital
  • Onji Morikazu
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon-city

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Abstract

A 27-year-old man was admitted due to abdominal fullness. He had ascites and subcutaneous nodules on his head, with liver dysfunction and eosinophilia. Abdominal imaging revealed obstruction of the hepatic veins and stenosis of the inferior vena cava. Histological diagnosis of a subcutaneous nodule revealed obstructive thrombophlebitis with eosinophils. Tyrosine kinase created by fusion of the FIP1L1 and PDGFRA genes, which is characteristic of hypereosinophilic syndrome (HES), was detected. He was diagnosed with Budd-Chiari syndrome associated with HES. Liver function tests improved after interventional therapy followed by steroid therapy. It is important to diagnose the cause of Budd-Chiari syndrome.<br>

Journal

  • Internal Medicine

    Internal Medicine 46 (14), 1095-1100, 2007

    The Japanese Society of Internal Medicine

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