Paraneoplastic Limbic Encephalitis Caused by Ovarian Teratoma with Autoantibodies to Glutamate Receptor

• Okamoto Sadahisa

  Department of Neurology, Graduate School of Medical Sciences, Kumamoto University

• Hirano Teruyuki

  Department of Neurology, Graduate School of Medical Sciences, Kumamoto University

• Takahashi Yukitoshi

  National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders

• Yamashita Taro

  Department of Neurology, Graduate School of Medical Sciences, Kumamoto University

• Uyama Eiichiro

  Department of Neurology, Graduate School of Medical Sciences, Kumamoto University

• Uchino Makoto

  Department of Neurology, Graduate School of Medical Sciences, Kumamoto University

Bibliographic Information

Other Title

• Paraneoplastic limbic encephalitis raised by ovarian teratoma with autoantibodies to glutamate receptor

Abstract

We report a rare case of paraneoplastic limbic encephalitis with autoantibodies to glutamate receptor (GluR) in the cerebrospinal fluid (CSF). The 35-year-old woman with consciousness disturbance was diagnosed initially as non-herpetic encephalitis. Her signs and symptoms improved with acyclovir and steroid pulse therapy. However, after the treatment, an ovarian tumor was discovered, and we detected autoantibodies to GluR in the CSF. A possible association between the ovarian teratoma and GluR is suggested.<br>

Journal

• Internal Medicine

  Internal Medicine 46 (13), 1019-1022, 2007

  The Japanese Society of Internal Medicine

Keywords

• paraneoplastic limbic encephalitis
• ovarian teratoma
• glutamate receptor

Details

• CRID: 1390001204872473088
• NII Article ID: 130000076160
• DOI: 10.2169/internalmedicine.46.6466
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/46/13/46_13_1019/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008064253
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed