A Clinical Evaluation of Definitive and Clinical Allergic Bronchopulmonary Mycosis

  • Matsuse Hiroto
    Second Department of Internal Medicine, Nagasaki University School of Medicine
  • Nakata Hiroko
    Second Department of Internal Medicine, Nagasaki University School of Medicine
  • Fukahori Susumu
    Second Department of Internal Medicine, Nagasaki University School of Medicine
  • Tsuchida Tomoko
    Department of Internal Medicine, Goto Central Hospital
  • Kawano Tetsuya
    Department of Internal Medicine, Senju Hospital
  • Tomari Shinya
    Department of Internal Medicine, Sasebo City General Hospital
  • Fukushima Chizu
    Department of Internal Medicine, Nagasaki Kita Hospital
  • Matsuo Nobuko
    Department of Internal Medicine, Nagasaki Municipal Medical Center
  • Asai Sadahiro
    Department of Internal Medicine, Sasebo City General Hospital
  • Kohno Shigeru
    Second Department of Internal Medicine, Nagasaki University School of Medicine

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Objective: The present study aims to overcome problems associated with the early diagnosis of allergic bronchopulmonary mycosis (ABPM) using the current criteria.<br> Patients and Methods: Clinical features including radiographic findings from 10 patients with definitive ABPM based on the diagnostic criteria of Rosenberg-Patterson were compared with those from 9 patients with ABPM clinically diagnosed by respiratory allergy specialists.<br> Results: ABPM should be considered in patients with peripheral blood eosinophilia and pulmonary infiltration and/or central bronchiectasis when serum total IgE is elevated. Complication by bronchial asthma suggested ABPM, but was not essential. The expectoration of sputum containing solid components was a critical factor in patients with a history in ABPM. Evaluation of sputum cultures, serum specific IgE antibodies, skin tests and precipitating antibodies were required to establish a diagnosis, but the positive rate of these tests remained low.<br> Conclusions: Even when a definitive diagnosis cannot be established, systemic corticosteroid therapy should be initiated for clinically diagnosed ABPM to prevent irreversible pulmonary dysfunction.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 45 (12), 759-762, 2006

    一般社団法人 日本内科学会

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