Clinical Outcome of Patients with SREDA (Subclinical Rhythmic EEG Discharge of Adults)

• Begum Tahamina

  Human Brain Research Center, Kyoto University Graduate School of Medicine

• Ikeda Akio

  Departments of Neurology, Kyoto University Graduate School of Medicine

• Takahashi Jun

  Departments of Neurosurgery, Kyoto University Graduate School of Medicine

• Tomimoto Hidekazu

  Departments of Neurology, Kyoto University Graduate School of Medicine

• Shimohama Shun

  Departments of Neurology, Kyoto University Graduate School of Medicine

• Satow Takeshi

  Human Brain Research Center, Kyoto University Graduate School of Medicine

• Nagamine Takashi

  Human Brain Research Center, Kyoto University Graduate School of Medicine

• Fukuyama Hidenao

  Human Brain Research Center, Kyoto University Graduate School of Medicine

• Shibasaki Hiroshi

  Human Brain Research Center, Kyoto University Graduate School of Medicine Departments of Neurology, Kyoto University Graduate School of Medicine Takeda General Hospital

Abstract

Objective: To clarify the clinical significance of subclinical rhythmic EEG discharge of adults' (SREDA) by analyzing characteristics of SREDA and the outcome of patients based on retrospective analysis of EEG data base.<br> Methods: EEGs were recorded soon after the onset of patient's initial symptoms and repeatedly recorded at various intervals of 23 months in all 4 patients. Neurological findings, MRI and SPECT were also investigated.<br> Subjects: Out of 340 consecutive inpatient population who had EEGs, 4 patients (1.2%) showed SREDA. They had a diagnosis of syncope, transient global amnesia, generalized tonicclonic seizure and right temporal lobe epilepsy for each.<br> Results: There was no consistent abnormality in the brain MRI, CT or SPECT among the 4 patients. The acute and transient symptoms disappeared and did not recur within the followup period of 28 months in any patient. In 2 patients SREDA disappeared in the followup EEG taken 714 days after the first EEG showing SREDA. In the other 2 patients, the followup EEGs taken 5 days after the first EEG with SREDA when clinical symptoms disappeared showed less frequent occurrence of SREDA.<br> Conclusion: Being different from the previous reports suggesting the relation with cardiogenic insults or persistent ischemic abnormality, SREDA can occur in patients with various acute brain dysfunctions followed by a favorable clinical outcome.<br>

Journal

• Internal Medicine

  Internal Medicine 45 (3), 141-144, 2006

  The Japanese Society of Internal Medicine

Keywords

• SREDA (subclinical rhythmic EEG discharge of adult)
• clinical correlates
• acute brain dysfunction
• outcome

Details

• CRID: 1390282679846134784
• NII Article ID: 130000076582
• DOI: 10.2169/internalmedicine.45.1479
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/45/3/45_3_141/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007217941
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed