Lymphoplasmacytic Infiltration of Multiple Organs with Immunoreactivity for IgG4: IgG4related Systemic Disease

• Saeki Takako

  Department of Internal Medicine, Nagaoka Red Cross Hospital

• Saito Akihiko

  Department of Applied Molecular Medicine, Niigata University Graduate School of Medical and Dental Sciences

• Hiura Tohru

  Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences

• Yamazaki Hajime

  Department of Internal Medicine, Nagaoka Red Cross Hospital

• Emura Iwao

  Department of Pathology, Nagaoka Red Cross Hospital

• Ueno Mitsuhiro

  Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences

• Miyamura Syoji

  Department of Internal Medicine, Nagaoka Red Cross Hospital

• Gejyo Fumitake

  Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences

抄録

We report three elderly men with high serum IgG4 concentrations and multiple lymphoplasmacytic inflammation of the salivary glands, lymph nodes, pancreas, and renal interstitium. The infiltrating plasma cells had strong immunoreactivity for IgG4, even in patients without pancreatic lesions. These cases show that IgG4 is associated not only with autoimmune pancreatitis, but also with other systemic lymphoplasmacytic disease.<br>

収録刊行物

• Internal Medicine

  Internal Medicine 45 (3), 163-167, 2006

  一般社団法人 日本内科学会

キーワード

• IgG4
• autoimmune pancreatitis
• Sjögren's syndrome
• Mikulicz's disease
• tubulointerstitial nephritis

詳細情報

• CRID: 1390001204869469440
• NII論文ID: 130000076587
• DOI: 10.2169/internalmedicine.45.1431
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/45/3/45_3_163/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2007217946
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可