Thyroid Crisis following Interstitial Nephritis

• Kahara Toshio

  Department of Internal Medicine, Toyama Prefectural Central Hospital

• Yoshizawa Miyako

  Department of Internal Medicine, Toyama Prefectural Central Hospital

• Nakaya Izaya

  Department of Internal Medicine, Toyama Prefectural Central Hospital

• Uchiyama Akio

  Department of Pathology, Toyama Prefectural Central Hospital

• Miwa Atsuo

  Department of Pathology, Toyama Prefectural Central Hospital

• Iwata Yasunori

  Department of Internal Medicine, Toyama Prefectural Central Hospital

• Torita Muneyoshi

  Department of Internal Medicine, Toyama Prefectural Central Hospital

• Usuda Rika

  Department of Internal Medicine, Toyama Prefectural Central Hospital

• Iida Hiroyuki

  Department of Internal Medicine, Toyama Prefectural Central Hospital

抄録

A 54-year-old man with Graves' disease had been treated with thiamazole (5 mg/day). His thyroid hormone level was increased after exodontia in February 2006. Although his prescribed dose of thiamazole was increased after exodontia on the fourth day, he developed thyroid crisis on exodontia 52nd day. Laboratory findings also showed renal dysfunction (from Cr 1.0 mg/dL in July 2005 to Cr 1.8 mg/dL on exodontia 37th day). His thyroid hormone level was normalized after subtotal thyroidectomy; however, serum Cr level was still high. He was diagnosed with interstitial nephritis as a result of renal biopsy, and he was treated with prednisolone 30 mg/day. This present case developed thyroid crisis even though the quantity of thiamazole was increased after exodontia. It seems that interstitial nephritis, as well as exodontia, is an aggravation factor of thyroid function. After a poor response to anti-thyroid drugs, it is necessary to prevent thyroid crisis by determining the aggravating factor and to then provide appropriate treatment.<br>

収録刊行物

• Internal Medicine

  Internal Medicine 47 (13), 1237-1240, 2008

  一般社団法人 日本内科学会

キーワード

• interstitial nephritis
• thyroid crisis
• hyperthyroidism
• Graves' disease

詳細情報

• CRID: 1390001204870466560
• NII論文ID: 130000078836
• DOI: 10.2169/internalmedicine.47.0947
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/47/13/47_13_1237/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2009001935
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可