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- HAUBITZ Marion
- Division of Nephrology, Department of Medicine, Hannover Medical School
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- WOYWODT Alexander
- Division of Nephrology, Department of Medicine, Hannover Medical School
この論文をさがす
抄録
Systemic vasculitides are a heterogeneous group of disorders with inflammation of blood vessels as their common pathogenetic hallmark. They often pose difficulties with regard to diagnosis and monitoring of disease activity, both at the initial presentation and during follow-up. Novel markers of disease activity are therefore eagerly awaited. Circulating endothelial cells have recently emerged as one such marker and we have demonstrated their clinical use in ANCA-associated small-vessel vasculitis. Not only entire cells but also endothelial microparticles can be detected in vasculitis although their use is not established to date. Repair of endothelial damage is believed to occur via endothelial progenitor cells and their precise role in vasculitis is also unclear at present. Circulating endothelial cells may complement, rather than replace, conventional markers of disease activity. The ultimate aim of our studies may thus be a panel of various laboratory markers for systemic vasculitis.
収録刊行物
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- Internal Medicine
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Internal Medicine 43 (8), 660-667, 2004
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390282679844898048
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- NII論文ID
- 130000084878
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- NII書誌ID
- AA10827774
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- COI
- 1:CAS:528:DC%2BD2cXhtVahsLbI
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 7059520
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- PubMed
- 15468962
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可