Body and Major Organ Weights of A/J-Chr 11SM Consomic Mice

• TANAKA Shin

  Animal Facility for Aging Research (AFAR), National Center for Geriatrics and Gerontology (NCGG)

• MIZOROGI Toshihiro

  Animal Facility for Aging Research (AFAR), National Center for Geriatrics and Gerontology (NCGG)

• NISHIJIMA Kazutoshi

  Animal Facility for Aging Research (AFAR), National Center for Geriatrics and Gerontology (NCGG)

• KUWAHARA Sachi

  Animal Facility for Aging Research (AFAR), National Center for Geriatrics and Gerontology (NCGG) Department of Anatomy, Hyogo College of Medicine

• TSUJIO Masashi

  Animal Facility for Aging Research (AFAR), National Center for Geriatrics and Gerontology (NCGG)

• AOYAMA Hiroaki

  Institute for Environmental Toxicology

• TAGUCHI Chie

  Laboratory of Animal Nutrition, Department of Applied Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University

• KOBAYASHI Misato

  Laboratory of Animal Nutrition, Department of Applied Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University

• HORIO Fumihiko

  Laboratory of Animal Nutrition, Department of Applied Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University

• OHNO Tamio

  Division of Experimental Animals, Center for Promotion of Medical Research and Education, Graduate School of Medicine, Nagoya University

Abstract

The body and major organ weights of A/J-Chr 11^SM consomic mice were compared to those of the progenitor strains, A/J and SM/J. The weights of the body and organs, except for those of the brain and uterus, were significantly greater in A/J mice than in SM/J mice. However, those of consomic mice were highly variable. For example, the average body weight of consomic mice was significantly greater than that of SM/J mice and nearly equal to that of A/J mice. Chromosome 11 of SM/J mice induced various significant changes of the organ weights of A/J mice, especially those of the brain, lung, kidney, adrenal, and ovary, demonstrating the importance of this chromosome in determining the phenotypes.<br>

Journal

• Experimental Animals

  Experimental Animals 58 (4), 357-361, 2009

  Japanese Association for Laboratory Animal Science

Keywords

• A/J
• chromosome 11
• consomic mice
• organ weight
• SM/J

Details

• CRID: 1390282680023723904
• NII Article ID: 130000122242
• NII Book ID: AA11032321
• DOI: 10.1538/expanim.58.357
• ISSN: 18817122
• ISSN: 00075124
• ISSN: 13411357
• NDL BIB ID: 10283420
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10283420
• Web Site: http://www.jstage.jst.go.jp/article/expanim/58/4/58_4_357/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed