Chiral Amidophosphane-Rhodium(I)-Catalyzed Asymmetric Conjugate Arylation of Acyclic Enones with Arylboronic Acids

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Author(s)

Abstract

A catalytic asymmetric conjugate arylation of acyclic α,β-unsaturated ketones with arylboronic acids was catalyzed by 3 mol% of chiral amidomonophosphane 1–rhodium(I) in the presence of potassium hydroxide in a mixture of 1,4-dioxane and water at 70 °C to afford 1,4-conjugate arylated acyclic ketones with high enantiomeric excess in high chemical yield. Thirteen examples of the reaction demonstrate the general applicability of the catalytic system.

Journal

  • Chemical and Pharmaceutical Bulletin

    Chemical and Pharmaceutical Bulletin 57(9), 1024-1027, 2009

    The Pharmaceutical Society of Japan

Codes

  • NII Article ID (NAID)
    130000124206
  • NII NACSIS-CAT ID (NCID)
    AA00602100
  • Text Lang
    ENG
  • ISSN
    0009-2363
  • NDL Article ID
    10332798
  • NDL Source Classification
    ZS51(科学技術--薬学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No.
    Z53-D167
  • Data Source
    NDL  J-STAGE 
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