健康維持・補完代替医療素材としての紅麹  [in Japanese] Red Koji (Red Mold Rice) for Complementary and Alternative Medicine as well as for Health Conditioning  [in Japanese]

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Abstract

紅麹は,古来より中国や韓国等でお酒をはじめとする種々発酵食品に用いられ,日本においても琉球王朝時代より豆腐ように用いられており,紅麹から抽出した「紅麹色素」は「天然着色剤」として普及している.また近年,一部の紅麹菌からコレステロール低下作用を有するロバスタチン(モナコリン K)が発見された.スタチン薬は LDL-コレステロール低下剤として今や世界中で約 3000 万もの人々に使用される処方薬であるが,この天然スタチンが含まれる紅麹を用いた加工食品も利用できるようになり,食生活改善による生活習慣病の一次予防においても注目される.本稿では,紅麹の食品としての歴史,機能性食品素材としての成分とその作用メカニズム,脂質代謝改善などの臨床試験結果などを取り上げ,補完代替医療素材としての可能性や健康維持・生活習慣病の予防における有用性について紹介する.<br>

Red koji has been used for a variety of fermentation food such as sake from old in China and South Korea, etc. and it has also been used from a Ryukyu dynasty for Tufuyo, a traditional bean curd food preparation in Okinawa in Japan, and “Red koji color (Monascus color)” extracted from Red koji is widespread as natural colorant.<br> Recently, lovastatin (Monacolin K) that has the hypocholesterolemic activity is discovered from a part of Red koji, though statins are prescription medicines used now for about 30 million people all over the world to decrease LDL-cholesterol that is the risk factor that causes atherosclerosis, and moreover the Red koji that contains this natural statin becomes available for the processed food such as dietary supplement, and it is expected a beneficial use in the primary care of the lifestyle disease by the eating habits improvement. In this paper, we would like to clarify the history as the food of Red koji, the active ingredients as the functional food material and the mechanism, the effectiveness and safety, including the clinical trial results such as improvement of lipid metabolism, and also introduce the probability as the beneficial material for complementary and alternative medicine as well as for dietary supplement in health conditioning and the prevention of the lifestyle disease.<br>

Journal

  • Japanese Journal of Complementary and Alternative Medicine

    Japanese Journal of Complementary and Alternative Medicine 6(2), 45-51, 2009

    The Japanese Society for Complementary and Alternative Medicine

Codes

  • NII Article ID (NAID)
    130000129032
  • NII NACSIS-CAT ID (NCID)
    AA12095429
  • Text Lang
    JPN
  • ISSN
    1348-7922
  • NDL Article ID
    10370488
  • NDL Source Classification
    ZS47(科学技術--医学--治療医学・看護学・漢方医学)
  • NDL Call No.
    Z74-E199
  • Data Source
    NDL  J-STAGE 
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