Anatomy: Gestational changes in production of NO and expression of NOS mRNA isoforms in the rat placenta
-
- SUZUKI Takehito
- Graduate School of Veterinary Medicine, Azabu University
-
- IKEDA Yoshinori
- Graduate School of Veterinary Medicine, Azabu University
-
- YOSHIKAWA Hiroshi
- Graduate School of Veterinary Medicine, Azabu University
-
- TANAKA Kazuaki
- Graduate School of Veterinary Medicine, Azabu University
-
- MORITA Hidetoshi
- Graduate School of Veterinary Medicine, Azabu University
-
- YAMAMOTO Masako
- Graduate School of Veterinary Medicine, Azabu University
-
- TAKIZAWA Tatsuya
- Graduate School of Veterinary Medicine, Azabu University Research Institute of Biosciences, Azabu University
書誌事項
- タイトル別名
-
- Gestational Changes in Production of NO and Expression of NOS mRNA Isoforms in the Rat Placenta
この論文をさがす
抄録
To monitor changes in NO production over time in the fetal placenta of rats, we used electron paramagnetic resonance spectroscopy with the Fe-N-(dithiocarboxy) sarcosine (Fe-DTCS) complex as an NO-trapping reagent. The expression of nitric oxide synthase (NOS) isoforms was examined in parallel using quantitative RT-PCR. NO production was first detected on day 13.5 of gestation. NO levels reached a peak on day 15.5, then decreased significantly during the last few days of gestation. The pattern of expression of NOS II mRNA was in good agreement with changes in NO levels, whereas NOS III mRNA expression did not change markedly during gestation. Thus, it appears that NO levels in the placenta are NOS II-dependent and differ at different gestational stages.<br>
収録刊行物
-
- Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ
-
Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ 71 (4), 495-498, 2009
公益社団法人 日本獣医学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001206427864320
-
- NII論文ID
- 130000134353
-
- NII書誌ID
- AA10796138
-
- ISSN
- 13477439
- 09167250
-
- NDL書誌ID
- 10279779
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可