ミトコンドリア内膜のADP/ATP透過担体のC末端領域の構造特性と機能  [in Japanese] Structural and Functional Properties of the C-terminal Region of Mitochondrial ADP/ATP Carrier  [in Japanese]

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Author(s)

Abstract

  Mitochondrial ADP/ATP carrier (AAC) is a protein catalyzing the transport of adenine nucleotides across inner mitochondrial membrane. In this review article, we first briefly introduce structural and functional properties of this protein. Next, we describe the results of our recent studies on the difference in the C-terminal region between yeast type 2 AAC isoform and bovine type 1 AAC isoform. Furthermore, based on the reactivities of cysteine residues that replaced amino acids in the sixth transmembrane segment, the probable structural features of the C-terminal region of this carrier are discussed.<br>

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 130(2), 199-204, 2010

    The Pharmaceutical Society of Japan

Codes

  • NII Article ID (NAID)
    130000171288
  • NII NACSIS-CAT ID (NCID)
    AN00284903
  • Text Lang
    JPN
  • ISSN
    0031-6903
  • NDL Article ID
    10545162
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-411
  • Data Source
    NDL  J-STAGE 
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