Medial temporal lobe epilepsy associated with cortical dysplasia extending from the medial temporal lobe to the fornix: a case report

• Morioka Takato

  Department of Neurosurgery, Kyushu Rosai Hospital

• Mukae Nobutaka

  Department of Neurosurgery, Kyushu Rosai Hospital

• Sayama Tetsuro

  Department of Neurosurgery, Kyushu Rosai Hospital

• Hamamura Takeshi

  Department of Neurosurgery, Kyushu Rosai Hospital

• Nomoto Asako

  Department of Radiology, Kyushu Rosai Hospital

• Yamamoto Kuniko

  Department of Clinical Laboratory, Kyushu Rosai Hospital

• Kido Tomomi

  Department of Clinical Laboratory, Kyushu Rosai Hospital

• Yamaguchi Tatsumi

  Yamaguchi Neurosurgical Clinic

• O Suzuki Satoshi

  Department of Neuropathology, Graduate School of Medical Sciences, Kyushu University

• Sasaki Tomio

  Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University

抄録

We report a case of lesional medial temporal lobe epilepsy (TLE) associated with cortical dysplasia extending from the right medial temporal lobe to the fornix via the basal and medial aspects of the frontal lobe and septum pellucidum. A 23-year-old man had had medically intractable psychomotor seizures since 11 years of age. Interictal EEG demonstrated paroxysmal activities in the right temporal region, and functional imaging by positron emission tomography with [18F] fluorodeoxyglucose revealed a functional deficit zone in the apex and medial part of the right temporal lobe. An intraoperative electrocorticogram demonstrated frequent paroxysmal activities in the medial temporal lobe. An anterior temporal lobectomy was performed, with an additional hippocampectomy including the focus of the paroxysmal activities on the intraoperative hippocampal EEG. Postoperatively, he became seizure-free. The surgical strategies for intractable TLE with widely distributed cortical dysplasia lesion are discussed.

収録刊行物

• Epilepsy & Seizure

  Epilepsy & Seizure 3 (1), 10-18, 2010

  一般社団法人 日本てんかん学会

キーワード

• medial temporal lobe epilepsy
• cortical dysplasia
• hippocampus
• fornix

詳細情報

• CRID: 1390282680267975808
• NII論文ID: 130000255356
• DOI: 10.3805/eands.3.10
• ISSN: 18825567
• Web Site: https://search.jamas.or.jp/link/ui/2012197970
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可