Severe Pneumonia Caused by a Novel Influenza A (H1N1) Virus in an Asymptomatic Emphysematous Smoker

Access this Article

Search this Article

Author(s)

    • Ozawa Hideki
    • Department of Internal Medicine, Tokai University School of Medicine
    • Miyachi Hayato
    • Department of Laboratory Medicine, Tokai University School of Medicine
    • Asai Satomi
    • Department of Laboratory Medicine, Tokai University School of Medicine
    • Jin Guilan
    • Department of Laboratory Medicine, Tokai University School of Medicine
    • Hasunuma Yuya
    • Department of Laboratory Medicine, Tokai University School of Medicine
    • Tanaka Chiharu
    • Department of Internal Medicine, Tokai University School of Medicine
    • Ikeda Takayuki
    • Department of Internal Medicine, Tokai University School of Medicine
    • Ueda Akihiro
    • Department of Internal Medicine, Tokai University School of Medicine

Abstract

A 49-year-old female presented with diarrhea and a high fever followed by progressive dyspnea. Until this presentation, she had been healthy except for chronic dyspepsia and diarrhea. She had a smoking habit of 15 pack-years. Laboratory tests revealed lymphopenia, hypoalbuminemia and hypogammaglobulinemia. A rapid influenza test in combination with an RT-PCR assay revealed the presence of the novel influenza A (H1N1) virus. Chest computed tomography revealed centrilobular emphysema. This report suggests that regular smoking may become a risk for severe pneumonia in patients presenting with the novel influenza A (H1N1) virus, when accompanying asymptomatic emphysema is combined with other problems such as hypoalbuminemia and hypogammaglobulinemia.<br>

Journal

  • Internal Medicine

    Internal Medicine 49(15), 1667-1670, 2010

    The Japanese Society of Internal Medicine

Cited by:  1

Codes

Page Top