Analysis of physicochemical properties of octacalcium phosphate prepared by hydrolysis and co-precipitation with fluoride ions

• SHIWAKU Yukari

  Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry

• HONDA Yoshitomo

  Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry

• ANADA Takahisa

  Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry

• MORIMOTO Shinji

  Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry

• MASUDA Taisuke

  Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry

• SASAKI Keiichi

  Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry

• SUZUKI Osamu

  Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry

Abstract

The present study was designed to determine the physicochemical properties of octacalcium phosphate (OCP) and its products obtained by different preparations in the presence of fluoride ions (F⁻) through hydrolysis of the synthesized OCP and co-precipitation. X-ray diffraction and chemical analyses of the products showed that OCP tended to be hydrolyzed into an apatitic structure in both preparations, while the OCP structure remained when hydrolyzed in alkaline pH and obtained by co-precipitation. The solubility decreased with increasing the F⁻ content in the hydrolyzed products but almost corresponded to that of the original OCP in the co-precipitation products. The results confirmed that the different preparation produces OCP hydrolyzates having distinct physicochemical properties that preserve the characteristics of OCP to some extent. Analysis of cytochrome c (used as a model protein of growth factors) adsorption onto the crystals indicated that the hydrolysis groups had the highest capacity to adsorb.

Journal

• Journal of the Ceramic Society of Japan

  Journal of the Ceramic Society of Japan 118 (1378), 402-405, 2010

  The Ceramic Society of Japan

Keywords

• Octacalcium phosphate
• Hydroxyapatite
• Fluoride
• Co-precipitation
• Hydrolysis
• Solubility
• Protein adsorption

Details

• CRID: 1390001205288337920
• NII Article ID: 130000304756
• NII Book ID: AA12229489
• DOI: 10.2109/jcersj2.118.402
• ISSN: 13486535
• ISSN: 18820743
• NDL BIB ID: 10690950
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10690950
• Web Site: http://www.jstage.jst.go.jp/article/jcersj2/118/1378/118_1378_402/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed